Foundayo (orforglipron) vs Saxenda (liraglutide)
Neither comes out ahead on the axes compared here. Foundayo scores higher on the published halfrx formula, 6.3 against 4.2; the formula takes in more than this table does.
Computed from the stored fields, so it moves when a price does. Nothing here is written by hand or by a model.
Foundayo (orforglipron) or Saxenda (liraglutide): which one has a price?
Only Foundayo (orforglipron) has an all-in figure here: $149–$349 a month, read from its own page on 2026-09-12. Saxenda (liraglutide) has none, so price cannot decide between them. Trial weight loss was 11.1% against 7.4%, from separate trials with different populations, so the gap is not a measured difference between the two. Every axis below is computed from stored fields rather than written by hand, so the comparison moves when a price does. Neither carries an FTC action, a state action, a BBB F grade or an FDA warning letter. The published formula scores them 6.3 and 4.2 out of 10, arithmetic over the same stored fields rather than an editor's preference. Cost here is scored on what a patient pays once titrated, never on the entry price, because an introductory rate covers the months before anybody has reached the dose they stay on.
Head to head
| What decides it | Foundayo $149–$349/mo | Saxenda price unverified |
|---|---|---|
| Entry priceNot comparable — Saxenda (liraglutide) publishes no verified all-in price. | not comparable | not comparable |
| Regulatory and complaint riskNeither carries a lawsuit, an FDA warning letter or a supply-risk flag. | tied | tied |
| Average weight loss in trialsFoundayo (orforglipron) reports 11.1% and Saxenda (liraglutide) 7.4%, each from its own trial. They were not compared against each other, and the populations, durations and endpoints differ, so the higher number is not a better result — it is a different study. | not comparable | not comparable |
What the trials, the titration and a year actually say
| Axis | Foundayo | Saxenda |
|---|---|---|
| Mean weight loss in the cited trial | 11.1% | 7.4% |
| The trial that figure comes from | ATTAIN-1, Trial 1 on the label, 72 weeks: 11.1% mean weight loss at 17.2 mg against 2.1% on placebo, intention-to-treat. | SCALE Obesity and Prediabetes, Study 1 on the label, 56 weeks: 7.4% mean weight loss on 3 mg against 3.0% on placebo, intention-to-treat. |
| Maintenance dose | 5.5 mg, 9 mg, 14.5 mg or 17.2 mg daily | 3 mg daily |
| Earliest week you reach it | week 9 | week 5 |
| Year one at the published price of every step | $3,188 | No titration prices recorded |
Trial percentages are quoted from the label or the named trial beside them. They are not a head-to-head result: different populations, different durations, different endpoints. That is why the comparison above scores this axis as not comparable rather than awarding it to the higher number. The year-one figures walk each titration step at its published price and count the twelve 30-day bottles a year holds. The full arithmetic is published.
What separates these two, price aside
- These are different molecules — orforglipron against liraglutide — so this is a comparison of two treatments, not of two prices for one.
Foundayo (orforglipron)
Pros
- +A daily pill with no injection, no needles and no refrigeration — unlike semaglutide pills it is a small molecule, so there are no food-and-water timing rules to follow.[3]
- +$149 a month at the entry dose through LillyDirect — the lowest self-pay price for a branded GLP-1 on this site, matched only by the Wegovy pill's first month.[4]
- +11.1% mean weight loss over 72 weeks in ATTAIN-1, intention-to-treat — below the Wegovy tablet's 13.6%, and well above the older oral options.[2]
- +Being a small molecule, it is manufactured chemically rather than biologically — supply scales in a way peptide injectables cannot.[3]
- +Commercially insured with coverage, Lilly's card can bring it to as little as $25 a month.[1]
Cons
- −Approved 1 April 2026, so real-world safety data outside trials is still thin compared with semaglutide's years of use.[2]
- −$649 list price if you have no coverage and do not use the LillyDirect self-pay channel.[4]
- −Weight loss trails tirzepatide injection, which reaches roughly 20%+ in its pivotal trials.[2]
- −Maintenance doses hold their $299 price only while you refill within 45 days; lapse and they are $349.[1]
Saxenda (liraglutide)
Pros
- +Longest safety record of any GLP-1 approved for weight, on the market since 2014.[1]
- +Generic liraglutide has been sold in the US since Teva launched generic Saxenda on 28 August 2025, so a branded Saxenda price is no longer the only liraglutide price.[3]
- +Approved for adolescents aged 12 and over, as Wegovy and Qsymia are; Zepbound is for adults only.[1]
Cons
- −7.4% mean weight loss on its label's trial — half of Wegovy and about a third of Zepbound.[1]
- −Daily injection rather than weekly. Seven times the injections for a worse result.[1]
- −No seller on this site offers branded Saxenda at a published cash price; Wegovy is $349 a month direct from NovoCare, for about twice the trial weight loss.[1]
Comparisons are computed from the fields on each card, not written by hand or by a model, so they change when the data does. Information only, not medical advice. halfrx may earn a commission from some links, which never changes what a comparison says.
Everything on Foundayo
- Foundayo price and terms →
- What is Foundayo? →
- Foundayo cost without insurance →
- Alternatives to Foundayo →
- Foundayo coupons and savings cards →
- Foundayo Self Pay Journey Program →
- Foundayo side effects →
- Does Foundayo make you feel sick? →
- Does Foundayo make you tired? →
- Does Foundayo cause constipation? →
- Does Foundayo cause diarrhea? →
- Does Foundayo make you throw up? →
- Does Foundayo cause hair loss? →
- Does Foundayo cause stomach pain? →
- Does Foundayo cause indigestion? →
- Does Foundayo cause acid reflux? →
- Does Foundayo make you burp? →
- Does Foundayo cause bloating? →
- Does Foundayo cause headaches? →
- Foundayo dose schedule →
- Can you stay on a lower dose of Foundayo? →
- How to take Foundayo →
- How long Foundayo takes to work →
- Which labels record what happens when you stop →
- Hair loss: which of the labels name it →
- Alcohol: what the labels say, and what they do not →
- orforglipron at LillyDirect: the price →
- orforglipron: every product and price →
- LillyDirect: the seller →
Everything on Saxenda
- Saxenda price and terms →
- What is Saxenda? →
- Saxenda cost without insurance →
- Alternatives to Saxenda →
- Saxenda side effects →
- Does Saxenda make you feel sick? →
- Does Saxenda make you tired? →
- Does Saxenda cause constipation? →
- Does Saxenda cause diarrhea? →
- Does Saxenda make you throw up? →
- Does Saxenda cause injection site reactions? →
- Does Saxenda cause stomach pain? →
- Does Saxenda cause indigestion? →
- Does Saxenda make you dizzy? →
- Does Saxenda cause headaches? →
- Does Saxenda cause low blood sugar? →
- Saxenda dose schedule →
- How to inject Saxenda →
- How long Saxenda takes to work →
- Which labels record what happens when you stop →
- Hair loss: which of the labels name it →
- Alcohol: what the labels say, and what they do not →
- liraglutide: every product and price →
- Hone Health: the seller →
- Victoza: the drug →
Foundayo against Saxenda, answered
- Is Foundayo or Saxenda better for weight loss?
- Foundayo reports 11.1% average weight loss and Saxenda 7.4%, each from its own trial. The two were not compared against each other, so the higher figure is not a result of a head-to-head and this page does not present it as one. What is comparable is what sits on each one's public record, below.
- Which is cheaper, Foundayo or Saxenda?
- Saxenda publishes no all-in monthly price that could be verified, so this page carries no comparison rather than an estimate — and an unpublished price is itself worth weighing.
- Can you switch between Foundayo and Saxenda?
- They are different molecules, so this is a change of medication rather than of brand, and the one you move to is started on its own dosing schedule.