Saxenda (liraglutide)
The first-generation GLP-1. Daily injection, half the weight loss, largely superseded.
- Medication
- brand
- Avg weight loss
- 7.4%
- Form
- injection
RxNorm 1598264 for the product, 475968 for the ingredient. The codes the US National Library of Medicine assigns, so this page names one specific thing rather than a brand that could mean several.
It carries a boxed warning — the strongest the FDA issues
In rodents this molecule caused thyroid C-cell tumors at human-relevant doses. Whether it does so in people is unknown, and the label carries that as a boxed warning. It is contraindicated outright with a personal or family history of medullary thyroid carcinoma or MEN 2.
From FDA prescribing information for SAXENDA. Everything the label lists, including who cannot take it →
No seller on this site offers branded Saxenda at a published cash price, and Novo Nordisk publishes none, so no price is shown. The $315 to $415 held here until 13 September 2026 came from Hone Health, whose men's weight-loss page sells compounded liraglutide, not Saxenda. Generic liraglutide has been sold in the US since Teva launched generic Saxenda on 28 August 2025.
What this page used to say
- 2026-09-13 — Saxenda's price. Was: $315 to $415 a month through telehealth. Now: No price shown: no seller on this site offers branded Saxenda at a published cash price.
- 2026-09-13 — Removed: Saxenda is tolerated less well than the weekly drugs. Was: A daily injection means the gastrointestinal effects arrive daily rather than weekly, which is one reason it is tolerated less well than the weekly drugs. Nausea, diarrhea, vomiting and constipation are the reason most people stop. They are worst in the first days after each dose increase and usually settle; a schedule held longer at one step is the standard answer, and it is a conversation with the prescriber rather than a reason to quit unannounced. Now: In the adult trials 9.8% of people on Saxenda stopped because of side effects, against 4.3% on placebo, most often for nausea (2.9%), vomiting (1.7%) or diarrhea (1.4%). If a dose increase is not tolerated, the label says to consider waiting about one more week before the next one, which is a conversation with the prescriber rather than a reason to quit unannounced.
- 2026-09-13 — Who may stay on 2.4 mg of Saxenda. Was: The recommended dose. Escalation in children can take up to 8 weeks, and 2.4 mg is allowed if 3 mg is not tolerated. Now: The recommended dose. For adults the lower doses are for titration only: an adult who cannot tolerate 3 mg stops Saxenda. Children 12 and older who cannot tolerate 3 mg may drop to 2.4 mg, and stop if that is not tolerated either; their escalation can take up to 8 weeks.
- 2026-09-12 — Why Saxenda costs what it does. Was: The daily injection is the cost driver: a month is 30 doses rather than 4, which is why Saxenda rarely undercuts the weekly drugs even where its list price looks lower. Now: Hone Health, the one seller halfrx records, charges $315 to $415 a month, and the price rises with the dose: $315 at the starting dose and $415 at maintenance. At $415 Saxenda costs more than Wegovy's $349 direct from NovoCare. The 30 daily injections a month change how often you inject, not the monthly price.
- 2026-09-12 — Generic liraglutide: on sale, not entering the market. Was: Generic liraglutide is now entering the market, which will push the price below every branded alternative. Now: Generic liraglutide has been sold in the US since Teva launched generic Saxenda on 28 August 2025, so a branded Saxenda price is no longer the only liraglutide price.
- 2026-09-11 — A point in its favor that no longer stood. Was: Approved for adolescents aged 12 and over, where the newer agents have narrower labels. Now: Approved for adolescents aged 12 and over, as Wegovy and Qsymia are; Zepbound is for adults only.
- 2026-09-11 — A drawback that no longer stood. Was: At $315+ through telehealth it costs more than Calibrate charges for branded Wegovy, which works far better. Now: At $315 to $415 a month through telehealth it costs about what Wegovy does direct from NovoCare, $349, for roughly half the trial weight loss.
- 2026-09-10 — A price no page could confirm, ninety-two days old. Was: $315–$415, checked 2026-06-10. Now: $315–$415, checked 2026-08-19.
- 2026-09-05 — Changed the trial figure to the intention-to-treat result on the FDA label. Was: SCALE: about 8% mean weight loss over 56 weeks. Now: 7.4% — SCALE Obesity and Prediabetes, Study 1 on the label, 56 weeks: 7.4% mean weight loss on 3 mg against 3.0% on placebo, intention-to-treat.
- 2026-09-05 — Added the label warning against sharing a pen between patients. Was: The serious reactions list did not mention pen sharing. Now: Never share a pen between patients, even with a new needle (5.9) — sharing risks passing on blood-borne infection.
- 2026-09-05 — Removed a suicidality warning and a pregnancy contraindication the label no longer carries, and corrected the common reactions on the side-effects page. Was: Serious: 'Suicidal behavior and ideation'. Contraindications included 'Pregnancy'. Common included 'reduced appetite' and an unqualified 'low blood sugar'. Now: Serious: the label's current section 5 headings, which add severe gastrointestinal reactions, hypersensitivity and pulmonary aspiration. Contraindications: MTC or MEN 2 history, and serious hypersensitivity to liraglutide. Common: 'reduced appetite' removed; 'low blood sugar in people with type 2 diabetes'.
- 2026-09-05 — Added the label's restart rule to the missed-dose answer on the dosage page. Was: Saxenda is daily, so a missed dose is simply skipped — take the next one at the usual time, and do not double up. Now: A single missed dose is skipped. If more than 3 days have passed since the last injection, the label says to restart at 0.6 mg and repeat the weekly escalation; the Medication Guide says to call the prescriber about how to restart.
How much does Saxenda (liraglutide) cost a month?
halfrx records no verified price for Saxenda (liraglutide): nothing it publishes states an all-in monthly figure, so this medication carries no price here rather than a guess. What it costs once titrated is not published, which is a fact about the seller rather than a gap in the data. It carries one flag on this site: boxed warning. A pharmacy acquires the same drug for about $1,307 a month under the federal NADAC survey, which is the comparison the price above is worth reading beside. It scores 4.2 out of 10 on a published formula that is arithmetic over the facts on this page, not an editor's opinion. Average weight loss in the trial cited on the page is 7.4%. The medication is the branded, FDA-approved product rather than a compounded copy. The page rests on 3 cited sources, at least one of them a manufacturer, regulator or journal. Molecule: liraglutide.
What it has cost
No clinician has reviewed this page. Label and trial statements are quoted from the FDA label or the trial cited beside them. General guidance is marked as such, and every price carries the date it was verified. That is sourcing, not medical review. What we do and do not check · Who checked the price
What is good about Saxenda?
- +Longest safety record of any GLP-1 approved for weight, on the market since 2014.[1]
- +Generic liraglutide has been sold in the US since Teva launched generic Saxenda on 28 August 2025, so a branded Saxenda price is no longer the only liraglutide price.[3]
- +Approved for adolescents aged 12 and over, as Wegovy and Qsymia are; Zepbound is for adults only.[1]
What are the downsides of Saxenda?
- −7.4% mean weight loss on its label's trial — half of Wegovy and about a third of Zepbound.[1]
- −Daily injection rather than weekly. Seven times the injections for a worse result.[1]
- −No seller on this site offers branded Saxenda at a published cash price; Wegovy is $349 a month direct from NovoCare, for about twice the trial weight loss.[1]
How this score is built
- 1.2/3.5Evidence — 7.4% mean weight loss, the intention-to-treat result on the FDA label
- 3.0/3Approval — FDA approved for chronic weight management
- 0.0/2.5Cost — no verified price
- 0.0/1Caveats — −1.0: weaker molecule −0.5, boxed warning −0.5
Clinical evidence
FDA approved for chronic weight management
SCALE Obesity and Prediabetes, Study 1 on the label, 56 weeks: 7.4% mean weight loss on 3 mg against 3.0% on placebo, intention-to-treat.
A pharmacy acquires this for about $1,307 a month under the federal NADAC survey. What that says about the price you are quoted →
How long Saxenda takes to work, and what each week costs →
What you can take instead of Saxenda, with each one's verified price →
What Saxenda costs without insurance, and every route to the same drug →
What the label says goes wrong, and who cannot take it →
Maintenance dose 3 mg daily, reachable no earlier than week 5. The full schedule, and what each step costs →
Compare Saxenda (liraglutide) with
Information only, not medical advice. Prices and terms change; the date above is when we last verified this one.
Everything on Saxenda
- Saxenda price and terms →
- What is Saxenda? →
- Saxenda cost without insurance →
- Alternatives to Saxenda →
- Saxenda side effects →
- Does Saxenda make you feel sick? →
- Does Saxenda make you tired? →
- Does Saxenda cause constipation? →
- Does Saxenda cause diarrhea? →
- Does Saxenda make you throw up? →
- Does Saxenda cause injection site reactions? →
- Does Saxenda cause stomach pain? →
- Does Saxenda cause indigestion? →
- Does Saxenda make you dizzy? →
- Does Saxenda cause headaches? →
- Does Saxenda cause low blood sugar? →
- Saxenda dose schedule →
- How to inject Saxenda →
- How long Saxenda takes to work →
- Which labels record what happens when you stop →
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- Saxenda vs Wegovy pill →
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- Ozempic vs Saxenda →
- Qsymia vs Saxenda →
- Saxenda vs Wegovy →
- Mounjaro vs Saxenda →
- Saxenda vs Zepbound →
- Hone Health: the seller →
- Victoza: the drug →