What is Foundayo approved for?

chronic weight management. Approvals are quoted from the label rather than summarised, because the wording is what a prior authorisation is judged against — the full text of each is on the indications page.

How much weight did Foundayo lose in its trial?

14.7% of body weight. ATTAIN-1, phase 3: mean 14.7% body weight lost at the highest dose over 72 weeks That is what one trial reported under its own protocol, not a prediction for any person, and it cannot be compared directly with another drug's figure because no trial ran them against each other.

How much does Foundayo cost?

$299 a month once titrated, read from the seller's own page on 2026-08-20. The starting dose is usually cheaper and nobody stays on it, which is why the maintenance figure is the one this site records.

What is Foundayo approved for?

chronic weight management. Approvals are quoted from the label rather than summarised, because the wording is what a prior authorisation is judged against — the full text of each is on the indications page.

How much weight did Foundayo lose in its trial?

14.7% of body weight. ATTAIN-1, phase 3: mean 14.7% body weight lost at the highest dose over 72 weeks That is what one trial reported under its own protocol, not a prediction for any person, and it cannot be compared directly with another drug's figure because no trial ran them against each other.

How much does Foundayo cost?

$299 a month once titrated, read from the seller's own page on 2026-08-20. The starting dose is usually cheaper and nobody stays on it, which is why the maintenance figure is the one this site records.

What is Foundayo?

What is Foundayo, and how does it work?

Foundayo (orforglipron) is a tablet made by Eli Lilly, whose active ingredient is orforglipron. FDA approved for chronic weight management A GLP-1 receptor agonist that works as a tablet rather than an injection, activating the same appetite-regulating receptor. In its pivotal trial it produced 14.7% mean weight loss. It costs $299 a month once titrated, a figure read from the seller's own page on 2026-08-20 — the maintenance rate rather than the starting dose, because the starting dose is not the dose anyone stays on.

How it works, from the label

A GLP-1 receptor agonist that works as a tablet rather than an injection, activating the same appetite-regulating receptor.

FOUNDAYO is a GLP-1 receptor agonist that binds to and activates the human GLP-1 receptor. GLP-1 is a physiological regulator of appetite and caloric intake. GLP-1 receptors are present in brain regions that regulate appetite. In animal studies, orforglipron distributed to and activated neurons in brain regions that regulate appetite and food intake.

Quoted from the mechanism of action section of FDA prescribing information for FOUNDAYO, read 2026-08-29. Not paraphrased: how a drug works is the last thing a price site should put in its own words.

What it is approved for

Chronic weight management
To reduce excess body weight and maintain weight reduction long term in adults with obesity, or adults with overweight in the presence of at least one weight-related comorbid condition.

Which approval a plan cannot exclude — a weight-loss exclusion is written against the use, not the molecule.

What the trial found

14.7% of body weight. ATTAIN-1, phase 3: mean 14.7% body weight lost at the highest dose over 72 weeks

One trial, one protocol, one population. Comparing it with another drug's figure compares two separate experiments rather than two drugs — the comparison, and what a point of body weight costs.

It carries a boxed warning — the strongest the FDA issues

In rodents this molecule caused thyroid C-cell tumours at human-relevant doses. Whether it does so in people is unknown, and the label carries that as a boxed warning. It is contraindicated outright with a personal or family history of medullary thyroid carcinoma or MEN 2.

Everything the label lists, including who cannot take it →

What it costs

$299 a month once titrated, read from the seller's own page on 2026-08-20. Definitional pages in this category stop before this line; it is the reason this one exists.

Foundayo price and terms →The cheapest way to get it →

Foundayo, answered

How does Foundayo work?: A GLP-1 receptor agonist that works as a tablet rather than an injection, activating the same appetite-regulating receptor. The label's own words, from its mechanism of action section: "FOUNDAYO is a GLP-1 receptor agonist that binds to and activates the human GLP-1 receptor. GLP-1 is a physiological regulator of appetite and caloric intake. GLP-1 receptors are present in brain regions that regulate appetite. In animal studies, orforglipron distributed to and activated neurons in brain regions that regulate appetite and food intake."
What is Foundayo approved for?: chronic weight management. Approvals are quoted from the label rather than summarised, because the wording is what a prior authorisation is judged against — the full text of each is on the indications page.
How much weight did Foundayo lose in its trial?: 14.7% of body weight. ATTAIN-1, phase 3: mean 14.7% body weight lost at the highest dose over 72 weeks That is what one trial reported under its own protocol, not a prediction for any person, and it cannot be compared directly with another drug's figure because no trial ran them against each other.
How much does Foundayo cost?: $299 a month once titrated, read from the seller's own page on 2026-08-20. The starting dose is usually cheaper and nobody stays on it, which is why the maintenance figure is the one this site records.

Last updated 2026-08-29 — the FDA label this page quotes