Alternatives to Trulicity
Bottom line
Nothing tracked here is the same medication as Trulicity, so every alternative is a different one. If you want cheaper, it is Qsymia at $75 a month against $389. Every price below carries its source and the date it was read, which is what separates this list from the others answering the same question.
No clinician has reviewed this page. Label and trial statements are quoted from the FDA label or the trial cited beside them. General guidance is marked as such, and every price carries the date it was verified. That is sourcing, not medical review. What we do and do not check · Who checked the price
Last updated 2026-09-22 — each alternative's published price. Read and dated by Alex Seot.
What can you take instead of Trulicity?
14 alternatives are tracked here, and none is the same medication as Trulicity in another product, so every one is a different medication, started on its own dosing schedule. On price the range runs $75 to $499 a month at the maintenance dose against $389 for Trulicity, every figure with its source and the date it was read beside it.
Best alternatives to Trulicity
Ordered by published trial weight loss, then by price. Every figure carries the date it was read.
1. Zepbound (tirzepatide)
The strongest approved weight-loss drug. $449/mo once titrated — or $699 if you ever miss the 45-day refill window.
- A month
- $449
- Trial weight loss
- 20.9%
- What it is
- branded, FDA approved
- Checked
- 2026-08-19, past 45 days
- A first year
- $5,637
Tirzepatide, not dulaglutide. $60 a month more expensive than Trulicity.
2. Wegovy (semaglutide)
$349/mo flat across every standard dose, with no refill deadline attached. Lilly's equivalent has one.
- A month
- $349
- Trial weight loss
- 14.9%
- What it is
- branded, FDA approved
- Checked
- 2026-09-22
- A first year
- $4,237
Semaglutide, not dulaglutide. $40 a month cheaper than Trulicity.
3. Wegovy pill (semaglutide)
The first GLP-1 pill approved for weight loss. NovoCare self-pay is $149 a month at 1.5 mg, $199 at 4 mg, and $299 at 9 mg and at the 25 mg dose you stay on.
- A month
- $299
- Trial weight loss
- 13.6%
- What it is
- branded, FDA approved
- Checked
- 2026-09-10
- A first year
- $3,338
Semaglutide, not dulaglutide. $90 a month cheaper than Trulicity.
4. Mounjaro (tirzepatide)
Zepbound's molecule under the diabetes label. Same drug, different box, different coverage rules.
- A month
- $499
- Trial weight loss
- 11.9%
- What it is
- branded, FDA approved
- Checked
- 2026-09-21
Tirzepatide, not dulaglutide. $110 a month more expensive than Trulicity.
5. Foundayo (orforglipron)
The first small-molecule GLP-1 pill. $149 to start, $299 once titrated, and no injection at any point.
- A month
- $299
- Trial weight loss
- 11.1%
- What it is
- branded, FDA approved
- Checked
- 2026-09-12
- A first year
- $3,188
Orforglipron, not dulaglutide. $90 a month cheaper than Trulicity.
6. Qsymia (phentermine, topiramate)
The strongest non-GLP-1 pill, at about 10% loss — with real pregnancy restrictions.
- A month
- $75
- Trial weight loss
- 9.8%
- What it is
- branded, FDA approved
- Checked
- 2026-09-22
Phentermine and topiramate, not dulaglutide. $314 a month cheaper than Trulicity.
7. Saxenda (liraglutide)
The first-generation GLP-1. Daily injection, half the weight loss, largely superseded.
- A month
- no verified price
- Trial weight loss
- 7.4%
- What it is
- branded, FDA approved
- Checked
- —
Liraglutide, not dulaglutide.
8. Ozempic (semaglutide)
Same molecule as Wegovy, approved for type 2 diabetes. $199 for two fills, then $349 to $499 a month.
- A month
- $349
- Trial weight loss
- 6.4%
- What it is
- branded, FDA approved
- Checked
- 2026-09-22
- A first year
- $4,237
Semaglutide, not dulaglutide. $40 a month cheaper than Trulicity.
9. Contrave (naltrexone, bupropion)
Non-GLP-1 oral option. Modest loss, but it is a pill and it is cheap.
- A month
- $99
- Trial weight loss
- 5.4%
- What it is
- branded, FDA approved
- Checked
- 2026-09-22
Naltrexone and bupropion, not dulaglutide. $290 a month cheaper than Trulicity.
10. Compounded tirzepatide (tirzepatide)
$199–$359/mo for the strongest molecule — with Eli Lilly suing the pharmacies that sell it.
- A month
- $199–$359 (no maintenance price)
- Trial weight loss
- not published
- What it is
- compounded, not FDA approved
- Checked
- 2026-09-13
Tirzepatide, not dulaglutide.
11. Phentermine (phentermine)
The cheapest weight-loss drug there is — approved for a few weeks, sold by subscription for years.
- A month
- no verified price
- Trial weight loss
- not published
- What it is
- generic
- Checked
- —
Phentermine, not dulaglutide.
12. Compounded semaglutide (semaglutide)
$129–$349/mo for the same molecule — and the reason it is cheap is the reason it is risky.
- A month
- $129–$349 (no maintenance price)
- Trial weight loss
- not published
- What it is
- compounded, not FDA approved
- Checked
- 2026-09-13
Semaglutide, not dulaglutide.
13. Victoza (liraglutide)
Daily liraglutide for type 2 diabetes — the same molecule as Saxenda at lower doses. No cash price published.
- A month
- no verified price
- Trial weight loss
- not published
- What it is
- branded, FDA approved
- Checked
- 2026-09-10
Liraglutide, not dulaglutide.
14. Rybelsus (semaglutide)
Novo publishes no cash price for Rybelsus, and the federal TrumpRx tablet is the Ozempic pill — a different strength on the same label.
- A month
- no verified price
- Trial weight loss
- not published
- What it is
- branded, FDA approved
- Checked
- 2026-09-07
Semaglutide, not dulaglutide.
Quick comparison
| Drug | A month | Trial loss | What it is | Checked |
|---|---|---|---|---|
| Trulicity (comparing against) | $389 | — | branded, FDA approved | 2026-09-22 |
| Zepbound | $449 | 20.9% | branded, FDA approved | 2026-08-19 |
| Wegovy | $349 | 14.9% | branded, FDA approved | 2026-09-22 |
| Wegovy pill | $299 | 13.6% | branded, FDA approved | 2026-09-10 |
| Mounjaro | $499 | 11.9% | branded, FDA approved | 2026-09-21 |
| Foundayo | $299 | 11.1% | branded, FDA approved | 2026-09-12 |
| Qsymia | $75 | 9.8% | branded, FDA approved | 2026-09-22 |
| Saxenda | — | 7.4% | branded, FDA approved | — |
| Ozempic | $349 | 6.4% | branded, FDA approved | 2026-09-22 |
| Contrave | $99 | 5.4% | branded, FDA approved | 2026-09-22 |
| Compounded tirzepatide | $199–$359 (no maintenance price) | — | compounded, not FDA approved | 2026-09-13 |
| Phentermine | — | — | generic | — |
| Compounded semaglutide | $129–$349 (no maintenance price) | — | compounded, not FDA approved | 2026-09-13 |
| Victoza | — | — | branded, FDA approved | 2026-09-10 |
| Rybelsus | — | — | branded, FDA approved | 2026-09-07 |
Trial figures come from each drug's own trial, so the column ranks published results rather than the drugs themselves. None of these drugs was compared against another in a head-to-head.
Where these Trulicity figures come from
Everything on Trulicity
- Trulicity price and terms →
- Trulicity cost without insurance →
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- Trulicity side effects →
- Does Trulicity make you feel sick? →
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- Does Trulicity cause stomach pain? →
- Does Trulicity take away your appetite? →
- Trulicity dose schedule →
- How to inject Trulicity →
- How long Trulicity takes to work →
- Which labels record what happens when you stop →
- Hair loss: which of the labels name it →
- Alcohol: what the labels say, and what they do not →
Alternatives to Trulicity, answered
- What is the closest alternative to Trulicity?
- Nothing tracked here is the same medication as Trulicity, so every alternative below is a different one, started on its own dosing schedule. What is comparable is the trial figure and the price, both listed with their sources.
- Is there a cheaper alternative to Trulicity?
- Yes. Qsymia is $75 a month against $389 for Trulicity — $314 a month less, or $3,768 across a year. Both figures are the maintenance price, each with its source and the date shown in the table.
- Does anything work better than Trulicity?
- No trial figure is recorded for Trulicity here, so this page does not rank it against anything on effect. Price and product status are what it can compare, and both are below.
Every price here carries its source and the date it was read, and anything past 45 days without a re-check is marked stale rather than quietly aging. Information only, not medical advice — which drug suits you is a question for a clinician.