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How to inject Trulicity

Taken once weekly, at any time of day, with or without food. Everything below is quoted from the FDA label rather than summarised, because a dosing instruction restated twice stops being the label and the detail that goes missing is always the number. What this page adds to the label is the part the label has no reason to carry: what a mistake costs.

How do you inject Trulicity, and what does getting it wrong cost?

Inject TRULICITY subcutaneously in the abdomen, thigh, or upper arm. Rotate injection sites with each dose. Storage is where the money is: the label allows 14 days out of the refrigerator, counted as a total rather than a run, and past it says to discard. At the maintenance rate stored on this site that is $389 thrown away — one pen, one month. On a missed dose the label is specific rather than permissive, and the window is short — the exact wording is below.

What the label says

Where it goes

Inject TRULICITY subcutaneously in the abdomen, thigh, or upper arm.

Rotating sites

Rotate injection sites with each dose.

Before use

Store TRULICITY in the refrigerator at 36°F to 46°F (2°C to 8°C).

Out of the fridge — 14 days

If needed, each single-dose pen can be kept at room temperature, not to exceed 86°F (30°C) for a total of 14 days.

Storage

Protect TRULICITY from light. Storage of TRULICITY in the original carton is recommended until time of administration.

Freezing

Do not freeze TRULICITY. Do not use TRULICITY if it has been frozen.

A missed dose

If a dose is missed, administer the missed dose as soon as possible if there are at least 3 days (72 hours) until the next scheduled dose.

Read from FDA prescribing information for TRULICITY on 2026-09-10. Labels are revised; the date is there so you can tell how old this reading is. Information only, not medical advice — dosing is a decision for the clinician who wrote the prescription.

What a mistake costs

  • A pen left out past 14 days: $389. The label says discard it, and nothing about a partial refund follows — that is a month of medication at the maintenance rate this site stores for Trulicity.
  • A frozen box: the same $389. The label is categorical about not using it, whatever it looks like afterwards.

No clinician has reviewed this page. Every clinical statement on it is drawn from the FDA label or the trial cited beside it, and every price carries the date it was verified — but that is sourcing, not medical review, and the two are not the same thing. What we do and do not check · Who checked the price

Injecting Trulicity, answered

Where do you inject Trulicity?
Inject TRULICITY subcutaneously in the abdomen, thigh, or upper arm. Rotate injection sites with each dose. That is the label's wording, not a summary of it. Nothing about the site changes the dose — the label sets no different dose for one site over another.
How long can Trulicity stay out of the fridge?
14 days, and the label states it as a total rather than a run: If needed, each single-dose pen can be kept at room temperature, not to exceed 86°F (30°C) for a total of 14 days. Past that the instruction is to discard, which is why this page carries a price at all — a discarded pen is $389 of medication at the maintenance rate stored here.
What if you miss a dose of Trulicity?
If a dose is missed, administer the missed dose as soon as possible if there are at least 3 days (72 hours) until the next scheduled dose.

Everything on Trulicity

Last updated 2026-09-10the FDA label this page quotes. Read and dated by Alex Seot.