Where do you inject Trulicity?

Where the label says, in its own words, in the passage above. Nothing about the site changes the dose — the label sets no different dose for one site over another.

How long can Trulicity stay out of the fridge?

14 days, in the label's words: If needed, each single-dose pen can be kept at room temperature, not to exceed 86°F (30°C) for a total of 14 days. A discarded single-dose pen is one week's dose, about $97 at the maintenance rate recorded here (price verified 2026-09-22).

How to inject Trulicity

Taken once weekly, at any time of day, with or without food. Everything below is quoted from the FDA label rather than summarized, because a dosing instruction restated twice stops being the label and the detail that goes missing is always the number. What this page adds to the label is the part the label has no reason to carry: what a mistake costs.

How do you inject Trulicity, and what does getting it wrong cost?

Inject TRULICITY subcutaneously in the abdomen, thigh, or upper arm. Rotate injection sites with each dose. Storage is where the money is: the label allows 14 days out of the refrigerator, counted as a total rather than a run, and past it the pen is not to be used. At the maintenance rate recorded on this site a discarded single-dose pen is about $97 (price verified 2026-09-22) — one week's dose. On a missed dose the label is specific rather than permissive — the exact wording is below.

What the label says

Where it goes

Inject TRULICITY subcutaneously in the abdomen, thigh, or upper arm.

Rotating sites

Rotate injection sites with each dose.

Before use

Store TRULICITY in the refrigerator at 36°F to 46°F (2°C to 8°C).

Out of the fridge — 14 days

If needed, each single-dose pen can be kept at room temperature, not to exceed 86°F (30°C) for a total of 14 days.

Storage

Protect TRULICITY from light. Storage of TRULICITY in the original carton is recommended until time of administration.

Freezing

Do not freeze TRULICITY. Do not use TRULICITY if it has been frozen.

A missed dose

If a dose is missed, instruct patients to administer the dose as soon as possible if there are at least 3 days (72 hours) until the next scheduled dose. If less than 3 days remain before the next scheduled dose, skip the missed dose and administer the next dose on the regularly scheduled day. In each case, patients can then resume their regular once weekly dosing schedule.

Read from FDA prescribing information for TRULICITY on 2026-09-12. Labels are revised; the date is there so you can tell how old this reading is. Information only, not medical advice — dosing is a decision for the clinician who wrote the prescription.

What a mistake costs

A pen left out past 14 days: about $97 (price verified 2026-09-22). It is a single dose, so that is one week's dose at the maintenance rate this site records for Trulicity, and nothing about a refund follows.
A frozen carton: $389 (price verified 2026-09-22), a month of medication at the maintenance rate. The label is categorical about not using it, whatever it looks like afterwards.

What Trulicity costs without insurance →The full Trulicity dose schedule →

No clinician has reviewed this page. Label and trial statements are quoted from the FDA label or the trial cited beside them. General guidance is marked as such, and every price carries the date it was verified. That is sourcing, not medical review. What we do and do not check · Who checked the price

Injecting Trulicity, answered

Where do you inject Trulicity?: Where the label says, in its own words, in the passage above. Nothing about the site changes the dose — the label sets no different dose for one site over another.
Does Trulicity need to be refrigerated?: Yes. The label's storage instruction: Store TRULICITY in the refrigerator at 36°F to 46°F (2°C to 8°C). Out of the fridge, the label allows 14 days.
How long can Trulicity stay out of the fridge?: 14 days, in the label's words: If needed, each single-dose pen can be kept at room temperature, not to exceed 86°F (30°C) for a total of 14 days. A discarded single-dose pen is one week's dose, about $97 at the maintenance rate recorded here (price verified 2026-09-22).
What if you miss a dose of Trulicity?: If a dose is missed, instruct patients to administer the dose as soon as possible if there are at least 3 days (72 hours) until the next scheduled dose. If less than 3 days remain before the next scheduled dose, skip the missed dose and administer the next dose on the regularly scheduled day. In each case, patients can then resume their regular once weekly dosing schedule.

Everything on Trulicity

Last updated 2026-09-12 — the FDA label this page quotes. Read and dated by Alex Seot.