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Trulicity (dulaglutide, diabetes label)

Trulicity (dulaglutide, diabetes label) dosage schedule

One injection a week, at any time of day, with or without food, escalated on the schedule in the FDA label below. The maintenance dose is 0.75 mg to 4.5 mg once weekly, and the earliest the label allows you to reach it is week 1.

Approved for type 2 diabetes, not for weight. Prescribing it for weight is off-label, which is legal, common, and where the insurance argument starts.

WhenDoseWhat the label says about it
1–40.75 mgStarting dosage, and one the label allows you to stay on.
5 and on1.5 mgOnly for additional glycaemic control.
9 at the earliest3 mgIncreases come in 1.5 mg steps, no sooner than every 4 weeks.
13 at the earliest4.5 mgMaximum recommended dosage.

Maximum dose: 4.5 mg once weekly. The label sets nothing above it.

What the escalation does to the bill

The dose changes and the bill does not: TrumpRx lists Trulicity at $389 a month for the single-dose pen at every strength, against a list price of $987.19. Every step above costs the same as the one before it.

halfrx records Trulicity (dulaglutide, diabetes label) at $389/mo, verified 2026-09-07 — and that figure is the maintenance dose, not the first month.

Missed dose

Take the missed dose as soon as possible if the next scheduled one is at least 3 days (72 hours) away. Otherwise skip it.

Side effects, from the same label →

No clinician has reviewed this page. Every clinical statement on it is drawn from the FDA label or the trial cited beside it, and every price carries the date it was verified — but that is sourcing, not medical review, and the two are not the same thing. What we do and do not check · Who checked the price

Everything on Trulicity

Questions

How long does it take to reach the maintenance dose of Trulicity?
At the fastest the label allows, week 1. Each step has to be held for its full interval before the next one, and a step can be repeated if the current dose is not tolerated — so the real answer is usually longer than the chart, never shorter.
What happens if I miss a dose?
Take the missed dose as soon as possible if the next scheduled one is at least 3 days (72 hours) away. Otherwise skip it.
Does the price change as the dose goes up?
The dose changes and the bill does not: TrumpRx lists Trulicity at $389 a month for the single-dose pen at every strength, against a list price of $987.19. Every step above costs the same as the one before it.

Every dose and interval on this page is from FDA prescribing information for TRULICITY (dulaglutide) , the version published 2026-08-10. Nothing here is a recommendation: the dose you take is the one your prescriber sets, and the schedule is often slowed deliberately for tolerability.