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Phentermine (generic) vs Saxenda (liraglutide)

Verdict

Saxenda (liraglutide) is the better choice of the two (halfrx score 5.4 against 3.1).

Computed from the stored fields, so it moves when a price does. Nothing here is written by hand or by a model.

Saxenda (liraglutide) or Phentermine (generic): which publishes a price?

Only one of these two publishes a verified all-in price, which settles the comparison before any other axis is reached: Saxenda (liraglutide) at $315–$415, and no figure at all for the other. Saxenda (liraglutide) is the better choice of the two (halfrx score 5.4 against 3.1). Every axis below is computed from stored fields rather than written by hand, so the comparison moves when a price does. Neither carries an FTC action, a state action, a BBB F grade or an FDA warning letter. One is generic and the other brand, which is the difference between an FDA-approved product and a copy made under the compounding exemption. The published formula scores them 3.1 and 5.4 out of 10, arithmetic over the same stored fields rather than an editor's preference.

Head to head

Phentermine (generic) against Saxenda (liraglutide), one row per axis, with the side that wins each axis marked.
What decides itPhentermine
price unverified
Saxenda
$315–$415/mo
Entry priceNot comparable — Phentermine (generic) publishes no verified all-in price.not comparablenot comparable
Regulatory and complaint riskNeither carries a lawsuit, state action or FDA-approval flag.levellevel
Brand vs compoundedSaxenda (liraglutide) supplies FDA-approved branded medication; Phentermine (generic) supplies compounded, which the FDA does not review for safety, efficacy or quality and which can stop shipping if its pharmacy is enjoined.levellevel

Read the price gap carefully: these two are not the same purchase

  • These are different molecules — Phentermine (generic) on phentermine, Saxenda (liraglutide) on liraglutide — so this is a comparison of two treatments, not of two prices for one.
Multiple generic manufacturers
Phentermine (generic)
3.1
Price unverified
Controlled substanceWeaker moleculeNo published priceStrict dosing rules
5.4
$315–$415/mo all-in
Checked 2026-06-10
Weaker molecule

Phentermine (generic)

Pros

  • +The cheapest drug in the category by two orders of magnitude: $0.068 a tablet at pharmacy acquisition cost against $263 for one Zepbound pen.[2]
  • +Covered by more Medicaid programmes than any GLP-1 — seven states cover an older weight-loss agent while covering no GLP-1 at all.[3]
  • +One tablet each morning, no injection, no titration schedule beyond a possible half dose.[1]

Cons

  • Approved for a few weeks only. Every monthly subscription selling it as ongoing therapy is using it off the label's own duration.[1]
  • Schedule IV controlled substance, chemically related to the amphetamines, with the dependence warnings that follow from that.[1]
  • Stopping after prolonged high dosing brings extreme fatigue and depression, per the label — which is a hard exit from a subscription that sold it as maintenance.[1]
  • No cardiovascular outcome data of the kind the GLP-1s now carry, and contraindicated where blood pressure is uncontrolled.[1]

Sources

  1. [1] FDA prescribing information for phentermine hydrochloride tablets, via DailyMed
  2. [2] NADAC (National Average Drug Acquisition Cost), CMS, file of 19 August 2026
  3. [3] KFF, Medicaid coverage of and spending on GLP-1s, January 2026

Saxenda (liraglutide)

Pros

  • +Longest safety record of any GLP-1 approved for weight, on the market since 2014.[1]
  • +Generic liraglutide is now entering the market, which will push the price below every branded alternative.[1]
  • +Approved for adolescents aged 12 and over, where the newer agents have narrower labels.[1]

Cons

  • About 8% mean weight loss — roughly half of Wegovy and well under half of Zepbound.[1]
  • Daily injection rather than weekly. Seven times the injections for a worse result.[1]
  • At $315+ through telehealth it costs more than Calibrate charges for branded Wegovy, which works far better.[1]

Sources

  1. [1] GLP-1 Telehealth Price Report 2026

Comparisons are computed from the fields on each card, not written by hand or by a model, so they change when the data does. Information only, not medical advice. halfrx may earn a commission from some links, which never changes what a comparison says.