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Compounded semaglutide vs Saxenda (liraglutide)

Verdict

Saxenda is the better choice of the two, winning on regulatory and complaint risk and approved product or compounded copy (halfrx score 4.2 against 1.9).

Computed from the stored fields, so it moves when a price does. Nothing here is written by hand or by a model.

Compounded semaglutide or Saxenda (liraglutide): which one has a price?

Only Compounded semaglutide has an all-in figure here: $129–$349 a month, the range its sellers here charge, oldest read 2026-09-13. Saxenda (liraglutide) has none, so price cannot decide between them. Every axis below is computed from stored fields rather than written by hand, so the comparison moves when a price does. Flags recorded here: Compounded semaglutide — not FDA approved, supply risk. Saxenda (liraglutide) is an FDA-approved product and Compounded semaglutide is a compounded copy made under the pharmacy-compounding exemption, which is a legal status rather than a quality claim. The published formula scores them 1.9 and 4.2 out of 10, arithmetic over the same stored fields rather than an editor's preference. Cost here is scored on what a patient pays once titrated, never on the entry price, because an introductory rate covers the months before anybody has reached the dose they stay on.

Head to head

Compounded semaglutide against Saxenda (liraglutide), one row per axis, with the side that wins each axis marked.
What decides itCompounded semaglutide
$129–$349/mo
Saxenda
price unverified
Entry priceNot comparable — Saxenda (liraglutide) publishes no verified all-in price.not comparablenot comparable
Regulatory and complaint riskCompounded semaglutide: 2 serious flags. Saxenda (liraglutide): none.—✓ better here
Approved product or compounded copySaxenda (liraglutide) supplies an FDA-approved product; Compounded semaglutide supplies a compounded preparation, which the FDA does not review for safety, efficacy or quality and which can stop shipping if its pharmacy is enjoined.—✓ better here
Compounded semaglutide publishes no page halfrx will send you toGo to Saxenda ↗

What separates these two, price aside

  • These are different molecules — semaglutide against liraglutide — so this is a comparison of two treatments, not of two prices for one.
503A/503B compounding pharmacies
Compounded semaglutide
1.9
$129–$349/mo all-in
checked 2026-09-13 — no maintenance-dose price
Not FDA approvedCompounding legal riskSupply risk
4.2
Price unverified
Weaker moleculeBoxed warning

Compounded semaglutide

Pros

  • +$129–$349 a month puts semaglutide within reach for people who would otherwise take nothing; branded semaglutide costs $299 a month for the Wegovy pill and $349 for the pens once past the starting doses.[1]
  • +Often shipped in vials with flexible dosing, so a provider can titrate in smaller steps than the fixed branded pen doses allow.[1]

Cons

  • −Not FDA approved. The agency does not review compounded drugs for safety, efficacy or manufacturing quality — potency and sterility depend entirely on the individual pharmacy.[1]
  • −The FDA declared the semaglutide shortage resolved, which removed the legal basis for mass compounding of copies. Providers now rely on 'personalized dose' arguments that Novo Nordisk is actively litigating.[2]
  • −Supply can stop mid-titration. A court order or state action against your compounder ends your prescription with no notice — in March 2025 Washington's Pharmacy Commission issued a limited stop-service order against Aequita, the Kirkland pharmacy that then supplied Mochi Health.[3]
  • −Some products are semaglutide salts (sodium or acetate) rather than the base molecule studied in trials. The FDA has warned these are different substances.[1]

Saxenda (liraglutide)

Pros

  • +Longest safety record of any GLP-1 approved for weight, on the market since 2014.[1]
  • +Generic liraglutide has been sold in the US since Teva launched generic Saxenda on 28 August 2025, so a branded Saxenda price is no longer the only liraglutide price.[3]
  • +Approved for adolescents aged 12 and over, as Wegovy and Qsymia are; Zepbound is for adults only.[1]

Cons

  • −7.4% mean weight loss on its label's trial — half of Wegovy and about a third of Zepbound.[1]
  • −Daily injection rather than weekly. Seven times the injections for a worse result.[1]
  • −No seller on this site offers branded Saxenda at a published cash price; Wegovy is $349 a month direct from NovoCare, for about twice the trial weight loss.[1]

Comparisons are computed from the fields on each card, not written by hand or by a model, so they change when the data does. Information only, not medical advice. halfrx may earn a commission from some links, which never changes what a comparison says.

Everything on Compounded semaglutide

Everything on Saxenda

The registers and documents behind both sides

Two cards compared on the same checks. These are the registers those checks were run against, and the FDA's own pages where either side is a compounded product.

Compounded semaglutide against Saxenda, answered

Is Compounded semaglutide or Saxenda better for weight loss?
Only Saxenda has a trial figure recorded here: 7.4% average weight loss, from its own label trial. Compounded semaglutide has none on this site — a compounded preparation has no trial of its own, so the two cannot be compared on effect and this page does not pick one on it.
Which is cheaper, Compounded semaglutide or Saxenda?
Saxenda publishes no all-in monthly price that could be verified, so this page carries no comparison rather than an estimate — and an unpublished price is itself worth weighing.
Can you switch between Compounded semaglutide and Saxenda?
They are different molecules, so this is a change of medication rather than of brand, and the one you move to is started on its own dosing schedule.
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