How to inject Wegovy
Taken once weekly, on the same day each week, at any time of day, with or without meals. Everything below is quoted from the FDA label rather than summarized, because a dosing instruction restated twice stops being the label and the detail that goes missing is always the number. What this page adds to the label is the part the label has no reason to carry: what a mistake costs.
How do you inject Wegovy, and what does getting it wrong cost?
Inject WEGOVY subcutaneously in the abdomen, thigh, or upper arm. The time of day and the injection site can be changed without the need for a dosage modification. Rotate injection sites with each dose. Storage is where the money is: for a single-dose pen or syringe, the label allows 28 days out of the refrigerator, and past it the pen is not to be used. At the maintenance rate recorded on this site a discarded single-dose pen is about $87 (price verified 2026-09-22) — one week's dose. A FlexTouch single-patient-use pen holds 4 doses and has its own clock: the label gives it 56 days after first use, at room temperature or in the refrigerator, and sets no limit in doses — four weekly doses run out at day 28, so the clock ends after the pen is empty rather than before. Missing doses can do more than skip one: if 2 or more consecutive doses of WEGOVY injection are missed, reinitiate dosage escalation at a lower dosage to reduce the risk of gastrointestinal adverse reactions. A restart does not raise the monthly bill here — no early dose on this ladder costs more than the maintenance rate — but it puts the weeks of escalation back in front of you.
What the label says
Where it goes
Inject WEGOVY subcutaneously in the abdomen, thigh, or upper arm. The time of day and the injection site can be changed without the need for a dosage modification.
Rotating sites
Rotate injection sites with each dose.
Before use
Store the WEGOVY prefilled single-dose pen or single-dose syringe in the refrigerator from 2°C to 8°C (36°F to 46°F).
Single-dose pen or syringe out of the fridge — 28 days
If needed, prior to the pen or syringe cap removal, the pen can be kept from 8°C to 30°C (46°F to 86°F) up to 28 days. Protect WEGOVY injection from light. WEGOVY injection must be kept in the original carton until time of administration.
FlexTouch single-patient-use pen — 56 days
Prior to first use, store WEGOVY FlexTouch single-patient-use pen in a refrigerator between 2°C to 8°C (36°F to 46°F). After first use, WEGOVY FlexTouch single-patient-use pen can be stored for 56 days between 15°C to 30°C (59°F to 86°F) or in a refrigerator 2°C to 8°C (36°F to 46°F).
Freezing
Do not freeze WEGOVY and do not use if it has been frozen.
A missed dose
Inform patients if a dose of WEGOVY injection is missed and the next scheduled dose is more than 2 days away (48 hours), administer WEGOVY injection as soon as possible. If one dose is missed and the next scheduled dose is less than 2 days away (48 hours), do not administer the dose. Inform patients to resume their regular once-weekly dosing schedule.
Missing more than one
If 2 or more consecutive doses of WEGOVY injection are missed, reinitiate dosage escalation at a lower dosage to reduce the risk of gastrointestinal adverse reactions.
Read from FDA prescribing information for WEGOVY on 2026-09-12. Labels are revised; the date is there so you can tell how old this reading is. Information only, not medical advice — dosing is a decision for the clinician who wrote the prescription.
What a mistake costs
- A single-dose pen or syringe left out past 28 days: about $87 (price verified 2026-09-22). It is a single dose, so that is one week's dose at the maintenance rate this site records for Wegovy, and nothing about a refund follows.
- A FlexTouch single-patient-use pen past its 56 days: whatever doses are left in it, up to four. The $349 (price verified 2026-09-22) recorded here is not a FlexTouch single-patient-use pen price, so there is no figure to give for one.
- A frozen carton: $349 (price verified 2026-09-22), a month of medication at the maintenance rate. The label is categorical about not using it, whatever it looks like afterwards.
- Enough missed doses to restart the escalation: no extra money a month on this ladder, since no early dose costs more than the $349 maintenance rate (price verified 2026-09-22) — the cost is the weeks spent climbing back.
No clinician has reviewed this page. Label and trial statements are quoted from the FDA label or the trial cited beside them. General guidance is marked as such, and every price carries the date it was verified. That is sourcing, not medical review. What we do and do not check · Who checked the price
Injecting Wegovy, answered
- Where do you inject Wegovy?
- Where the label says, in its own words, in the passage above. Nothing about the site changes the dose — the label says explicitly that the time of day and the injection site can be changed without a dosage modification.
- Does Wegovy need to be refrigerated?
- Yes. The label's storage instruction: Store the WEGOVY prefilled single-dose pen or single-dose syringe in the refrigerator from 2°C to 8°C (36°F to 46°F). Out of the fridge, the label allows 28 days for a single-dose pen or syringe.
- How long can Wegovy stay out of the fridge?
- 28 days for a single-dose pen or syringe, in the label's words: If needed, prior to the pen or syringe cap removal, the pen can be kept from 8°C to 30°C (46°F to 86°F) up to 28 days. Protect WEGOVY injection from light. WEGOVY injection must be kept in the original carton until time of administration. A discarded single-dose pen is one week's dose, about $87 at the maintenance rate recorded here (price verified 2026-09-22). A FlexTouch single-patient-use pen holds 4 doses and runs on a different clock, 56 days: the label gives it 56 days after first use, at room temperature or in the refrigerator, and sets no limit in doses — four weekly doses run out at day 28, so the clock ends after the pen is empty rather than before. The label's words: Prior to first use, store WEGOVY FlexTouch single-patient-use pen in a refrigerator between 2°C to 8°C (36°F to 46°F). After first use, WEGOVY FlexTouch single-patient-use pen can be stored for 56 days between 15°C to 30°C (59°F to 86°F) or in a refrigerator 2°C to 8°C (36°F to 46°F). The doses still in it are lost, up to four. The $349 (price verified 2026-09-22) recorded here is not a FlexTouch single-patient-use pen price, so there is no figure to give for one.
- What if you miss a dose of Wegovy?
- Inform patients if a dose of WEGOVY injection is missed and the next scheduled dose is more than 2 days away (48 hours), administer WEGOVY injection as soon as possible. If one dose is missed and the next scheduled dose is less than 2 days away (48 hours), do not administer the dose. Inform patients to resume their regular once-weekly dosing schedule. After a longer gap: If 2 or more consecutive doses of WEGOVY injection are missed, reinitiate dosage escalation at a lower dosage to reduce the risk of gastrointestinal adverse reactions.
- Does restarting the escalation cost more?
- Not per month. No step before maintenance on this ladder is priced above the $349 maintenance rate (price verified 2026-09-22), so the months spent climbing back cost the same or less. What a restart costs is time: the escalation is repeated from the lower dose the label sets, and those are weeks below the dose you had reached. The per-dose figures are on the cost page for this drug.
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Last updated 2026-09-12 — the FDA label this page quotes. Read and dated by Alex Seot.