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How to inject Ozempic

Taken once weekly. Everything below is quoted from the FDA label rather than summarised, because a dosing instruction restated twice stops being the label and the detail that goes missing is always the number. What this page adds to the label is the part the label has no reason to carry: what a mistake costs.

How do you inject Ozempic, and what does getting it wrong cost?

Inject OZEMPIC subcutaneously in the abdomen, thigh, or upper arm. Storage is where the money is: the label allows 56 days out of the refrigerator, counted as a total rather than a run, and past it says to discard. At the maintenance rate stored on this site that is $199 thrown away — one pen, one month. On a missed dose the label is specific rather than permissive, and the window is short — the exact wording is below.

What the label says

Where it goes

Inject OZEMPIC subcutaneously in the abdomen, thigh, or upper arm.

Before use

Prior to first use, the OZEMPIC pen should be stored in a refrigerator between 2°C to 8°C (36°F to 46°F).

Out of the fridge — 56 days

After first use of the OZEMPIC pen, the pen can be stored for 56 days at controlled room temperature 15°C to 30°C (59°F to 86°F) or in a refrigerator 2°C to 8°C (36°F to 46°F).

Freezing

Do not freeze OZEMPIC and do not use OZEMPIC if it has been frozen.

A missed dose

If a dose is missed, administer within 5 days of missed dose.

Read from FDA prescribing information for OZEMPIC (semaglutide) injection on 2026-08-28. Labels are revised; the date is there so you can tell how old this reading is. Information only, not medical advice — dosing is a decision for the clinician who wrote the prescription.

What a mistake costs

  • A pen left out past 56 days: $199. The label says discard it, and nothing about a partial refund follows — that is a month of medication at the maintenance rate this site stores for Ozempic.
  • A frozen box: the same $199. The label is categorical about not using it, whatever it looks like afterwards.

Injecting Ozempic, answered

Where do you inject Ozempic?
Inject OZEMPIC subcutaneously in the abdomen, thigh, or upper arm. That is the label's wording, not a summary of it. Nothing about the site changes the dose — the label sets no different dose for one site over another.
How long can Ozempic stay out of the fridge?
56 days, and the label states it as a total rather than a run: After first use of the OZEMPIC pen, the pen can be stored for 56 days at controlled room temperature 15°C to 30°C (59°F to 86°F) or in a refrigerator 2°C to 8°C (36°F to 46°F). Past that the instruction is to discard, which is why this page carries a price at all — a discarded pen is $199 of medication at the maintenance rate stored here.
What if you miss a dose of Ozempic?
If a dose is missed, administer within 5 days of missed dose.

Everything on Ozempic

Last updated 2026-08-28the FDA label this page quotes