Tirzepatide
Bottom line
The same substance costs $178 a month at its cheapest verified route and $499 at its dearest — 2.8 times as much, a gap of $321 a month or $3,852 a year. Which product it is sold as changes the approved indication and the dose ceiling, not the molecule.
Last updated 2026-06-10 — every published price for this molecule
What is tirzepatide, and what does it cost?
Tirzepatide is sold as Zepbound, Mounjaro, Compounded tirzepatide — the same active substance under different approved indications and different dose ceilings, which is why switching between them is a prescribing decision rather than a change of medication. halfrx records 6 verified routes to it, from $178 a month at Mochi Health to $499 at Mounjaro, which is 2.8 times the price for the same molecule. Each figure is the all-in maintenance price — membership plus medication where a seller bundles them — read from that seller's own published page on the date beside it. On trial evidence the best published result for this molecule is 20.9% average weight loss, from the trial behind Zepbound; no head-to-head has compared it against another molecule, so that ranks a published result rather than the drug. Its FDA label lists nausea, fatigue, constipation, diarrhoea, vomiting, hair loss, injection site reactions among the common reactions, each with its own page here. A compounded preparation of the same molecule is a different legal product rather than a discount on the approved one: compounding is an exemption from approval, so it carries no trial and no approved label of its own.
Every verified route, cheapest first
Products and sellers together, because the question is what the molecule costs rather than which shelf it sits on.
| Route | A month | What it is | Trial loss | Checked |
|---|---|---|---|---|
| Mochi Health | $178 | compounded, not FDA approved | — | 2026-08-19 |
| Compounded tirzepatide | $200 | compounded, not FDA approved | — | 2026-06-10, past 45 days |
| Noom Med | $249 | compounded, not FDA approved | — | 2026-08-20 |
| LillyDirect | $299 | provider | — | 2026-08-20 |
| Zepbound | $449 | direct from the maker | 20.9% | 2026-08-19 |
| Mounjaro | $499 | direct from the maker | 15% | 2026-08-24 |
The products tirzepatide is sold as
1. Zepbound
The strongest approved weight-loss drug. $449/mo once titrated — or $699 if you ever miss the 45-day refill window.
- A month
- $449
- A first year
- $5,637
- Trial loss
- 20.9%
- FDA status
- FDA approved for chronic weight management and obstructive sleep apnea
2. Mounjaro
Zepbound's molecule under the diabetes label. Same drug, different box, different coverage rules.
- A month
- $499
- Trial loss
- 15%
- FDA status
- FDA approved for type 2 diabetes. Weight loss is off-label use.
3. Compounded tirzepatide
$125–$278/mo for the strongest molecule — with Eli Lilly suing the pharmacies that sell it.
- A month
- $200
- Trial loss
- not published
- FDA status
- Not FDA approved. Compounded drugs are not reviewed by the FDA for safety, efficacy or quality.
What every tirzepatide label lists, and each on its own page
These reactions appear on the FDA label of Zepbound, Mounjaro — the same molecule, so the same list.
- Does Zepbound make you feel sick?
- Does Zepbound make you tired?
- Does Zepbound cause constipation?
- Does Zepbound cause diarrhoea?
- Does Zepbound make you throw up?
- Does Zepbound cause hair loss?
- Does Zepbound cause injection site reactions?
Boxed warning. In rodents this molecule caused thyroid C-cell tumours at human-relevant doses. Whether it does so in people is unknown, and the label carries that as a boxed warning. It is contraindicated outright with a personal or family history of medullary thyroid carcinoma or MEN 2.
Savings programmes across tirzepatide
- Medicare GLP-1 Bridge
$50 a month — Centers for Medicare & Medicaid Services
- Mounjaro Savings Card
As little as $25 for a 1-, 2- or 3-month fill — Eli Lilly
- Zepbound Journey Program
$449 a month at 7.5 mg and above — Eli Lilly
- Zepbound savings card
As little as $25 for up to a 3-month prescription — Eli Lilly
Tirzepatide, answered
- What is the cheapest tirzepatide?
- Mochi Health at $178 a month all-in once titrated, read from its own published page on 2026-08-19. The dearest verified route to the same molecule is Mounjaro at $499 — 2.8 times the price for the same substance.
- Which products contain tirzepatide?
- Zepbound, Mounjaro, Compounded tirzepatide. They differ by approved indication and by dose ceiling rather than by active substance, which is why a switch between them is a prescribing decision rather than a change of medication.
- Is compounded tirzepatide the same as the branded version?
- Same molecule, different legal product. Compounding is an exemption from FDA approval rather than a form of it, so a compounded preparation has no trial and no approved label of its own, and its quality is a fact about the pharmacy that mixes it. No seller on this site names that pharmacy — all eleven checked, with the pages read listed at /pharmacy.
- How much weight do people lose on tirzepatide?
- 20.9% on average in the trial behind Zepbound, SURMOUNT-1: about 20.9% mean weight loss at the 15 mg dose over 72 weeks. That figure describes one trial population under one protocol; no head-to-head trial has compared these molecules against each other, so it ranks published results rather than the drugs.
Every price is read from the seller's own published page on the date shown; anything past 45 days without a re-check is marked stale rather than quietly aging. Label information from FDA prescribing information for ZEPBOUND. Information only, not medical advice.