Tirzepatide
Bottom line
The same substance costs $249 a month at its cheapest verified route and $499 at its most expensive — 2.0 times as much. That is a gap of $250 a month, or $3,000 a year. Which product it is sold as changes the approved indication and the dose ceiling, not the molecule.
No clinician has reviewed this page. Label and trial statements are quoted from the FDA label or the trial cited beside them. General guidance is marked as such, and every price carries the date it was verified. That is sourcing, not medical review. What we do and do not check · Who checked the price
Last updated 2026-09-22 — every published price for this molecule. Read and dated by Alex Seot.
What is tirzepatide, and what does it cost?
Tirzepatide is sold as Zepbound, Mounjaro and Compounded tirzepatide — the same active substance under different approved indications and different dose ceilings, which is why switching between them is a prescribing decision rather than a change of medication. halfrx records 7 verified routes to it, from $249 a month at Noom Med to $499 at Mounjaro, which is 2.0 times the price for the same molecule. Each figure is the all-in maintenance price — membership plus medication where a seller bundles them — each with its source and the date it was read beside it. On trial evidence the best published result for this molecule is 20.9% average weight loss, from the trial behind Zepbound. That is a label figure; the trials that put it against another molecule are SURMOUNT-5 (weight fell 20.2% on tirzepatide against 13.7% on semaglutide over 72 weeks, in adults with obesity); SURPASS-2 (tirzepatide lost 1.9 to 5.5 kg more than semaglutide 1 mg over 40 weeks, in type 2 diabetes). Between them its FDA labels list nausea, fatigue, constipation, diarrhea, vomiting, hair loss, injection site reactions, abdominal pain, indigestion, reflux, burping and decreased appetite among the common reactions — not every label lists every one — each with its own page here. A compounded preparation of the same molecule is a different legal product rather than a discount on the approved one: compounding is an exemption from approval, so it carries no trial and no approved label of its own.
Where can I buy tirzepatide?
Every verified route, cheapest first: products and sellers together, because the question is what the molecule costs rather than which shelf it sits on.
| Route | A month | What it is | Trial loss | Checked |
|---|---|---|---|---|
| Noom Med | $249 | compounded, not FDA approved | — | 2026-09-22 |
| Found | $289 | compounded, not FDA approved | — | 2026-09-22 |
| Henry Meds | $297 | compounded, not FDA approved | — | 2026-09-20 |
| LillyDirect | $299 | provider | — | 2026-09-13 |
| Medvi | $299 | provider | — | 2026-09-14 |
| Zepbound | $449 | direct from the maker | 20.9% | 2026-08-19, past 45 days |
| Mounjaro | $499 | direct from the maker | 11.9% (from kg) | 2026-09-21 |
The products tirzepatide is sold as
1. Zepbound
The strongest approved weight-loss drug. $449/mo once titrated — or $699 if you ever miss the 45-day refill window.
- A month
- $449
- A first year
- $5,637
- Trial loss
- 20.9%
- FDA status
- FDA approved for chronic weight management and obstructive sleep apnea
2. Mounjaro
Zepbound's molecule under the diabetes label. Same drug, different box, different coverage rules.
- A month
- $499
- Trial loss
- 11.9% (from kg)
- FDA status
- FDA approved for type 2 diabetes: to improve glycemic control, and on the label revised August 2026 also to reduce the risk of cardiovascular death, heart attack and stroke in adults with type 2 diabetes at high risk of them. Weight loss is off-label use.
3. Compounded tirzepatide
$199–$359/mo for the strongest molecule — with Eli Lilly suing the pharmacies that sell it.
- A month
- no verified price
- Trial loss
- not published
- FDA status
- Not FDA approved. Compounded drugs are not reviewed by the FDA for safety, efficacy or quality.
What the tirzepatide labels list, and each on its own page
Each reaction below is listed among the common adverse reactions on at least one of these FDA labels — Mounjaro and Zepbound. The labels do not all list the same ones, so each line names the labels that do.
- Does Mounjaro make you feel sick?
Listed on all 2 labels
- Does Zepbound make you tired?
Listed on Zepbound
- Does Mounjaro cause constipation?
Listed on all 2 labels
- Does Mounjaro cause diarrhea?
Listed on all 2 labels
- Does Mounjaro make you throw up?
Listed on all 2 labels
- Does Zepbound cause hair loss?
Listed on Zepbound
- Does Zepbound cause injection site reactions?
Listed on Zepbound
- Does Mounjaro cause stomach pain?
Listed on all 2 labels
- Does Mounjaro cause indigestion?
Listed on all 2 labels
- Does Zepbound cause acid reflux?
Listed on Zepbound
- Does Zepbound make you burp?
Listed on Zepbound
- Does Mounjaro take away your appetite?
Listed on Mounjaro
Boxed warning. In rodents this molecule caused thyroid C-cell tumors at human-relevant doses. Whether it does so in people is unknown, and the label carries that as a boxed warning. It is contraindicated outright with a personal or family history of medullary thyroid carcinoma or MEN 2.
Savings programs across tirzepatide
- Medicare GLP-1 Bridge
$50 a month — Centers for Medicare & Medicaid Services
- Mounjaro Savings Card
As little as $25 for a 1-, 2- or 3-month fill — Eli Lilly
- Zepbound Journey Program
$449 a month at 7.5 mg and above — Eli Lilly
- Zepbound savings card
As little as $25 for up to a 3-month prescription — Eli Lilly
Tirzepatide, answered
- What is the cheapest tirzepatide?
- Noom Med at $249 a month all-in once titrated, read from its own published page on 2026-09-22. The most expensive verified route to the same molecule is Mounjaro at $499 — 2.0 times the price for the same substance.
- Which products contain tirzepatide?
- Zepbound, Mounjaro and Compounded tirzepatide. They differ by approved indication and by dose ceiling rather than by active substance, which is why a switch between them is a prescribing decision rather than a change of medication.
- Is compounded tirzepatide the same as the branded version?
- Same molecule, different legal product. Compounding is an exemption from FDA approval rather than a form of it, so a compounded preparation has no trial and no approved label of its own, and its quality is a fact about the pharmacy that mixes it. No seller on this site names that pharmacy — all eleven checked, with the pages read listed at /pharmacy.
- How much weight do people lose on tirzepatide?
- 20.9% on average in the trial behind Zepbound, SURMOUNT-1, Study 1 on the label, 72 weeks: 20.9% mean weight loss at 15 mg against 3.1% on placebo, intention-to-treat. That figure describes one trial population under one protocol. Against other molecules it has been tested head to head in SURMOUNT-5 (weight fell 20.2% on tirzepatide against 13.7% on semaglutide over 72 weeks, in adults with obesity); SURPASS-2 (tirzepatide lost 1.9 to 5.5 kg more than semaglutide 1 mg over 40 weeks, in type 2 diabetes).
Every price carries its source and the date it was read; anything past 45 days without a re-check is marked stale rather than quietly aging. Label information from FDA prescribing information for MOUNJARO. Information only, not medical advice.